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Attributes for classification of mouse strains in the leprosy spectrum
| Characteristic | B6 | 10NOS2−/− | NOS2−/− | IFN‐γ−/− | Athymic nude |
|---|---|---|---|---|---|
| ML growth | + | + | + | ++ | +++ |
| Granuloma | Minimal | Destructive | Destructive | Unorganized | Leproma |
| FP induration | + | +++ | +++ | ++ | − |
| Lymphoid cells | CD4 > CD8 | ↑CD4↑CD8 | ↑CD4 | ↑CD4 | − |
| Myeloid cells | Epithelioid | Epithelioid | Epithelioid | ↓MΦ/↑PMN | Foamy |
| Cytokine response | TH1 | ↑TH1 | ↑TH1 | TH2/TH17 | TH2 |
| Classification | Self‐healing | TT | BT | BL | LL |
