Figure 3.
Schematic overview of the most described mechanisms involved in interactions between fibrotic stroma and macrophages. Hypothesised involvement of signalling pathways/molecules is illustrated with dashed frames. Upregulated pro‐inflammatory markers are depicted in blue, and profibrotic/anti‐inflammatory in red. Arg‐1, arginase‐1; FAK, focal adhesion kinase; TRPV4, transient receptor potential vanilloid type 4; YAP, Yes‐associated protein.