Fig. 3.

Some proposed future directions of 3D genomics research in plants. There are many possible directions of 3D genomic research using different plant samples at different scales, such as the identification of large‐scale structural variation between different plants, construction of dynamic 3D genome maps in plant cell differentiation and organ development, and 3D genome analysis from a tissue sample to a single cell. The research field of 3D genomics in plants will be expanded, for example to understand the mechanisms of 3D genome folding, the effects of transposon expansion on shaping 3D genome architecture, the spatial haplotype chromatin interaction, and the CRISPR‐based functional analysis of enhancers and boundaries of TAD‐like structures.