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. 2021 Mar 22;61(3):422–429. doi: 10.1111/head.14089

TABLE 3.

Primary efficacy endpoint outcomes by triptan historical experience (mITT population)

Pooled ACHIEVE participants
Placebo Ubrogepant 50 mg
(n = 912) (n = 887)
Triptan naive
Pain freedom at 2 h, n/N (%) 61/339 (18) 78/327 (24)
Absence of MBS at 2 h, n/N (%) 105/338 (31) 132/325 (41)
Triptan responders
Pain freedom at 2 h, n/N (%) 40/350 (11) 67/331 (20)
Absence of MBS at 2 h, n/N (%) 94/349 (27) 129/332 (39)
Triptan‐insufficient responders
Pain freedom at 2 h, n/N (%) 18/223 (8) 37/228 (16)
Absence of MBS at 2 h, n/N (%) 52/223 (23) 81/226 (36)

Abbreviations: MBS, most bothersome migraine‐associated symptom; mITT, modified intent‐to‐treat.