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Frequency of changes in immunophenotype of leukemic blasts. (A-C) Frequency of changes in immunophenotype of leukemic blasts in relapsed cases (A), cases with detectable blasts in bone marrow only at a minimal residual disease level (B), and in resistant cases (C). Cases of “lineage switch” are not shown. *Differences in frequencies of antigen expression changes are statistically significant (P<0.05). MRD: minimal residual disease; MFC: multicolor flow cytometry.
