Table 2. Pharmacokinetic parameters after i.v. administration of CUR-NSps and CUR injections.
CUR-NSps | CUR injections | |
---|---|---|
t1/2 (h) | 65.07 ± 30.88** | 1.81 ± 1.56 |
Cmax (ng/mL) | 1467.08 ± 215.06** | 3696.13 ± 311.57 |
AUClast (h*ng/mL) | 7672.04 ± 2594.79* | 1704.69 ± 122.52 |
Cl (mL/h/kg) | 209.42 ± 164.61** | 3822.45 ± 976.68 |
MRT (h) | 9.45 ± 3.28** | 0.50 ± 0.04 |
The results are presented as mean ± SD, n = 10.
p < 0.05 versus CUR injections.
p < 0.01 versus CUR injections.