Table 3. AUC_0–24 h, MRT and C_max of the biodistribution of CUR-NSps and CUR injections.

	AUC0–24 h/h·μg·mL−1		MRT/h		Cmax/μg·mL−1
	CUR-NSps	CUR injections	CUR-NSps	CUR injections	CUR-NSps	CUR injections
Heart	134.28 ± 13.67*	203.25 ± 27.04	11.25 ± 0.26	9.96 ± 1.03	6.85 ± 0.14	19.00 ± 1.35
Liver	7.33 ± 0.44***	3.52 ± 0.24	11.15 ± 0.21*	8.44 ± 1.13	0.40 ± 0.02	0.41 ± 0.06
Spleen	419.70 ± 27.25**	319.03 ± 13.83	13.55 ± 0.53	14.19 ± 0.61	25.30 ± 3.36	20.30 ± 1.23
Lung	84.87 ± 9.95	96.28 ± 29.29	12.27 ± 1.24	9.11 ± 2.90	6.03 ± 1.87	17.94 ± 3.84
Kidney	37.61 ± 1.85**	27.22 ± 1.57	12.13 ± 0.32	11.99 ± 0.90	1.72 ± 0.07*	1.41 ± 0.16
Brain	301.17 ± 5.31*	263.37 ± 19.57	11.91 ± 0.47	11.78 ± 0.47	14.07 ± 0.52	13.69 ± 0.14
Tumor	3.56 ± 0.04**	2.70 ± 0.27	12.21 ± 0.20	11.78 ± 0.47	0.16 ± 0.01***	0.13 ± 0.01

The results are presented as mean ± SD, n = 10.

*p < 0.05 vs CUR injections.

**p < 0.01 vs CUR injections.

***p < 0.001 vs CUR injections.