Table 5.
Multivariable adjusted multinomial logistic regression analysis for the associations of demographic and clinical relevant factors with trajectories eGFR decline.
| Variables | Gradual eGFR decline (Group 2) n = 69 |
Early rapid eGFR decline (Group 3) n = 156 |
Rapid eGFR decline (Group 4) n = 84 |
||||||
|---|---|---|---|---|---|---|---|---|---|
| β | aOR (95%CI) | p-Value | β | aOR (95%CI) | p-Value | β | aOR (95%CI) | p-Value | |
| Age (<75 vs.≥75 years) | 0.011 | 1.011 (0.491–2.082) | 0.975 | 0.234 | 1.264 (0.691–2.310) | 0.447 | 0.837 | 2.310 (1.104–4.832) | 0.026* |
| Gender (female vs. male) | 0.466 | 1.593 (0.765–3.316) | 0.213 | 0.480 | 1.616 (0.873–2.992) | 0.127 | 1.136 | 3.113 (1.475–6.570) | 0.003* |
| Diabetes (yes vs. no) | 0.535 | 1.707 (0.826–3.530) | 0.149 | 0.461 | 1.585 (0.863–2.913) | 0.138 | 0.895 | 2.448 (1.159–5.171) | 0.019* |
| uPCr ≥ 3.5 (g/g) at baseline | 1.557 | 4.743 (0.948–23.741) | 0.058 | 1.621 | 5.058 (1.130–22.64) | 0.034* | 2.389 | 10.91 (2.298–51.75) | 0.003* |
| Cognitive impairment (yes vs. no) | 0.439 | 1.551 (0.531–4.529) | 0.422 | 0.193 | 1.213 (0.472–3.117) | 0.689 | 1.291 | 3.636 (1.330–9.942) | 0.012* |
| Hospitalized within 1-year before dialysis (yes vs. no) | 0.475 | 1.608 (0.742–3.482) | 0.229 | 0.745 | 2.106 (1.104–4.017) | 0.024* | 0.902 | 2.466 (1.077–5.645) | 0.033* |
Values show the risk profile (aOR) for each trajectory group compared to trajectory Group 1 (slower decline). Predictors starred* are those that were statistically significant. aOR, adjusted odds ratio in relation to all the other variables in the table; CI, confidence interval.