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. 2021 Jul 1;10(1):1309–1319. doi: 10.1080/22221751.2021.1908098

Figure 4.

Figure 4.

Evaluation of the role of overexpression of SLY in the non-epidemic S. suis strain P1/7 on STSLS with a murine model. (A) Cytokine levels in the blood at 6 h post-infection were determined (n = 4). (B) The bacterial load in the blood at 6 h post-infection was determined (n = 4). (C) Blood levels of AST, ALT, LDH, and CK at 6 h post-infection were determined (n = 4). (D) H&E staining of infected tissue sections from mice at 6 h post-infection with S. suis strains. Congestion in the lung and spleen is indicated by a “red arrow”, infiltration of inflammatory cells in the lung is indicated by a “blue arrow”, vacuolated degeneration in the liver is indicated by a “black arrow”, and necrosis in the liver is indicated by a “yellow arrow”. (E) Clinical symptom scores of mice infected with S. suis strains (n = 8). (F) Survival of mice infected with S. suis strains (n = 8). Error bars represented the mean ± standard deviations.