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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: J Pediatr. 2020 May 11;224:102–109.e3. doi: 10.1016/j.jpeds.2020.05.001

Table VIII.

Prevalence, unadjusted, and adjusted odds of recent opioid misuse by category and number of ACEs, adjusting for sociodemographics and lifetime history of nonopioid substance use (n = 10 293), Northeast Ohio Youth Health Survey, 2018

Opioid misuse in the past 30 d
ACEs Prevalence, % Unadjusted OR (95% CI) aOR (95% CI)

Lifetime misuse of alcohol*
 No 0.6 1.0 1.0
 Yes 3.5 6.4 (4.5–9.2) 1.9 (1.1–3.3)
Lifetime misuse of marijuana*
 No 0.8 1.0 1.0
 Yes 6.8 8.5 (6.1–11.8) 1.6 (0.99–2.7)
Lifetime misuse of other substances*,
 No 0.7 1.0 1.0
 Yes 16.8 27.2 (19.7–37.6) 13.6 (9.3–19.8)
Emotional abuse
 No 1.0 1.0 1.0
 Yes 4.9 5.0 (3.9–6.5) 1.9 (1.5–2.5)
Physical abuse
 No 1.2 1.0 1.0
 Yes 6.6 5.8 (4.3–7.8) 1.9 (1.5–2.4)
Sexual abuse
 No 1.3 1.0 1.0
 Yes 8.9 7.3 (5.4–9.9) 2.2 (1.7–3.0)
Witnessed intimate partner violence
 No 1.5 1.0 1.0
 Yes 7.5 5.3 (3.9–7.3) 1.7 (1.2–2.4)
Household substance abuse
 No 1.2 1.0 1.0
 Yes 4.8 4.0 (3.1–5.1) 1.4 (1.1–1.9)
Mental illness in household
 No 1.1 1.0 1.0
 Yes 4.5 4.2 (3.2–5.5) 1.8 (1.4–2.3)
Parental separation or divorce
 No 1.4 1.0 1.0
 Yes 2.5 1.8 (1.3–2.4) 1.0 (0.7–1.4)
Incarcerated household member
 No 1.2 1.0 1.0
 Yes 4.6 3.8 (2.9–5.0) 1.5 (1.2–1.9)
Physical neglect
 No 1.6 1.0 1.0
 Yes 9.9 6.7 (4.6–9.9) 1.9 (1.2–2.9)
Emotional neglect
 No 1.0 1.0 1.0
 Yes 5.5 5.6 (4.1–7.6) 2.2 (1.6–3.1)
Number of ACEs
 0 0.5 1.0 1.0
 1 0.9 2.0 (0.9–4.3) 1.6 (0.8–3.2)
 ≥1 2.7 5.7 (3.4–9.4) 2.1 (1.3–3.6)
 2 2.0 4.3 (2.0–9.3) 2.1 (1.04–4.3)
 3 2.1 4.4 (2.5–7.7) 1.9 (1.1–3.4)
 4 3.3 7.0 (3.4–14.5) 2.2 (1.1–4.6)
 ≥5 7.9 17.7 (10.2–30.7) 3.5 (2.1–5.9)
*

ORs adjusted for sex; race; grade; lifetime misuse of alcohol, marijuana, other substance use; sexual minority status; and exposure to ≥1 ACEs.

Self-reported use of synthetic marijuana, cocaine, ecstasy, glue/huffing, prescription muscle relaxers or anxiety medicine without a doctor’s prescription at least once in participant’s lifetime.

ORs adjusted for sex; race; grade; lifetime misuse of alcohol, marijuana, other substance use; and sexual minority status.