Table 1.
Cohort characteristics.
| Lean (n = 12) | Centrally Obese (n = 12) | |
|---|---|---|
| Characteristics | ||
| Age (years) | 35.8 ± 10.6 | 34.8 ± 7.4 |
| Stature (cm) | 177.4 ± 5.3 | 181.5 ± 5.3 |
| Body mass (kg) | 74.7 ± 7.2 | 111.1 ± 12.1* |
| Body mass index (kg/m2) | 23.7 ± 1.8 | 33.7 ± 2.4* |
| Waist circumference (cm) | 80.4 ± 6.4 | 110.2 ± 10.1* |
| Hip circumference (cm) | 95.4 ± 4.6 | 114.2 ± 10.8* |
| Waist-to-hip ratio | 0.84 ± 0.04 | 0.97 ± 0.07* |
| SBP (mmHg) | 118 ± 9.3 | 134.4 ± 8.6* |
| DBP (mmHg) | 70.7 ± 6.8 | 81.3 ± 7.9* |
| Fasting Metabolic Variables | ||
| Fasting glucose (mmol/L) | 4.40 ± 0.26 | 4.56 ± 0.4 |
| Fasting insulin (pmol/L) | 51.58 ± 17.14 | 101.94 ± 45.41* |
| HOMA-IR | 1.68 ± 0.56 | 3.40 ± 1.40* |
| GLP-1 (pmol/L) | 17.29 ± 4.63 | 25.78 ± 9.24* |
| GLP-1 ACTIVE (pmol/L) | 0.79 ± 0.40 | 0.78 ± 0.53 |
| GLP-1 ACTIVE/TOTAL (pmol/L) | 0.05 ± 0.03 | 0.03 ± 0.02* |
| GIP (pmol/L) | 11.01 ± 5.60 | 11.42 ± 4.67 |
| TC (mmol/L) | 4.22 ± 0.85 | 3.85 ± 0.66 |
| HDL (mmol/L) | 1.21 ± 0.27 | 0.95 ± 0.10* |
| Tg (mmol/L) | 1.15 ± 0.24 | 1.60 ± 0.37* |
DBP, diastolic blood pressure; GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like peptide 1; HDL, high-density lipoprotein; HOMA-IR, homeostatic model assessment—insulin resistance; SBP, systolic blood pressure; TC, total cholesterol; Tg, triglycerides.
Data presented are mean averages from duplicate measurements taken during both trials. Lipid markers were measured from each participant’s first trial.
All data is presented as mean ± SD.
*Denotes a statistical significance between groups as determined by an independent samples t test or a Mann–Whitney U Test (p <0.05).