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. 2021 Jun 18;11:648988. doi: 10.3389/fcimb.2021.648988

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Copyright © 2021 Wu, Zhang, Yang, Cui, Zhang, Xiao and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The analysis of the innate immune pathway-related proteins. (A) Venn diagrams depict the differential proteins in innate immune pathway after 12 h and 24 h stimulation by heat-killed C. albicans versus the M group. (B) The average fold changes of 20 differential proteins for those significantly regulated in at least one comparison group (Y-12 h versus M: # or Y-24 h versus M: ▲) were analyzed. The fold changes of proteins were logarithmic transformed. (C) Correlation matrix of innate immune pathway-related proteins. (D) Selected the up-regulated GLUT3 and down-regulated (ITGAM/CD11B, ITGB2/CD18, CD14 and CASP8) in the innate immune pathway are shown. ***P < 0.001; **P < 0.01; *P < 0.05.