FIGURE 2.

5‐Aminolevulinic acid (5‐ALA)/sodium ferrous citrate (SFC) increased the tumor‐infiltrating activated programmed cell death‐1 (PD‐1)⁺Tim‐3⁻ T lymphocyte population. A, Mean percentages of CD4⁺PD‐1⁺Tim‐3⁻ and CD8⁺PD‐1⁺Tim‐3⁻ cells among CD3⁺ tumor‐infiltrating lymphocyte T cells. B, Mean percentages of CD4⁺PD‐1⁺Tim‐3⁻ and CD8⁺PD‐1⁺Tim‐3⁻ cells among CD3⁺ spleen cells. Data represent the mean ± SD. *P < .05, by a one‐way ANOVA with Tukey’s multiple comparisons test