TABLE 1.
Characteristics | NACRT | US | NACRT vs US |
---|---|---|---|
N = 40 | N = 30 | P value | |
Age (y) | 66 (51‐78) | 68 (52‐84) | .44 |
Male gender | 24 (65%) | 16 (53%) | .28 |
Pretreatment diagnosis: R/BR/LA | 3 (8%)/35 (88%)/2 (5%) | 14 (47%)/16 (53%)/0 | <.01 |
Procedure: SSPPD(TP)/DP | 31 (79%)/9 (22%) | 19 (63%)/11 (37%) | .15 |
Poor differentiation | 4 (10%) | 0 | .07 |
ypTS | 2.7 (0.9‐5.5) | 2.9 (1.0‐4.3) | .14 |
Nodal metastasis | 12 (40%) | 24 (80%) | <.01 |
Stage IA/IB/IIA/IIB/III | 10 (25%)/17 (43%)/1 (3%)/9 (23%)/3 (8%) | 3 (10%)/5 (17%)/0/16 (53%)/6 (20%) | .01 |
Treatment effect, Evans grade I/IIA/IIB/III | 9 (19%)/20 (50%)/8 (20%)/3 (8%) | ‐ | ‐ |
Resection margin–negative | 34 (85%) | 23 (77%) | .28 |
Recurrence | 28 (70%) | 20 (67%) | .77 |
Abbreviations: BR, borderline resectable; DP, distal pancreatectomy; LA, locally advanced; NACRT, neoadjuvant chemoradiotherapy; R, resectable; SSPPD, subtotal stomach‐preserving pancreatoduodenectomy; TP, total pancreatectomy; US, upfront surgery.