TABLE 4.
Comparison of basic characteristics between pancreatic ductal adenocarcinoma (PDAC) patients with high or low macrophage infiltration in cancer cell nests
| Characteristics | High CD204+ (cancer cell nest) | Low CD204+(cancer cell nest) | High vs low |
|---|---|---|---|
| N = 20 | N = 20 | P‐value | |
| Age (y) | 66 (51‐78) | 66 (54‐78) | .34 |
| Male gender | 14 (70%) | 10 (50%) | .17 |
| Pretreatment diagnosis: R/BR/LA | 2 (10%)/16 (80%)/2 (10%) | 1 (5%)/19 (95%)/0 | .27 |
| Procedure: SSPPD(TP)/DP | 31 (79%)/9 (22%) | 19 (63%)/11 (37%) | .15 |
| Poor differentiation | 2 (10%) | 2 (10%) | 1.00 |
| ypTS | 2.5 (0.9‐5.5) | 3.0 (1.0‐4.0) | .51 |
| Nodal metastasis | 4 (20%) | 8 (40%) | .17 |
| Resection margin–negative | 3 (15%) | 3 (15%) | 1.00 |
| Recurrence | 16 (80%) | 12 (60%) | .15 |
Abbreviations: BR, borderline resectable; DP, distal pancreatectomy; LA, locally advanced; R, resectable; SSPPD, subtotal stomach‐preserving pancreatoduodenectomy; TP, total pancreatectomy; ypTS, pathological tumor size.