Figure 4.
Trend plots of tracer levels in different brain locations of the IIH and REF cohorts. The trend plots of percentage change in tracer enrichment (normalized signal unit ratio) reveal significantly higher tracer levels in enrichment and clearance phases in the IIH than the REF group. This was shown for cerebral cortex grey matter in A, cerebral white matter in B, cerebellar cortex (grey matter) in C, cerebellar white matter in D, basal ganglia in E and brainstem in F. Trend plots are presented with mean ± standard error (SE). Statistical differences: *P < 0.05, **P < 0.01 and ***P < 0.001 (linear mixed models).