Skip to main content
. 2021 Mar 21;3(2):fcab043. doi: 10.1093/braincomms/fcab043

Figure 5.

Figure 5

Increased CSF tracer levels in selected limbic structures of IIH patients indicative of reduced molecular clearance. The trend plots of percentage change in tracer enrichment (normalized signal unit ratio) reveal significantly stronger tracer enrichment in enrichment and clearance phases in IIH as compared to REF groups for several brain regions belonging to the limbic system. The regions included amygdala in A, hippocampus in B, parahippocampal cortex (grey matter) in C, parahippocampal white matter in D, entorhinal cortex (grey matter) in E and entorhinal subcortex (white matter) in F. Trend plots are presented with mean ± standard error (SE). Statistical differences: *P < 0.05, **P < 0.01 and ***P < 0.001 (linear mixed models).