Table 7. IHC expression of EMT-related markers vs. tumor deposits.
Tumor Deposits | ||||
---|---|---|---|---|
Absent | Present | p-value | ||
Number | 104 | 38 | ||
E-cadherin | 0.004* | |||
+1 | 1 (0.96) | 4 (10.53) | ||
+2 | 13 (12.50) | 9 (23.68) | ||
+3 | 90 (86.54) | 25 (65.79) | ||
β-catenin | 0.736 | |||
0 | 46 (44.66) | 18 (47.37) | ||
+1 | 33 (32.04) | 9 (23.68) | ||
+2 | 21 (20.39) | 9 (23.68) | ||
+3 | 3 (2.91) | 2 (5.26) | ||
Claudin-1 | 0.007* | |||
0 | 4 (3.85) | 8 (21.05) | ||
+1 | 40 (38.46) | 9 (23.68) | ||
+2 | 43 (41.35) | 17 (44.74) | ||
+3 | 17 (16.35) | 4 (10.53) | ||
CD44 | 0.346 | |||
0 | 5 (4.85) | 5 (13.16) | ||
+1 | 35 (33.98) | 10 (26.32) | ||
+2 | 46 (44.66) | 16 (42.11) | ||
+3 | 17 (16.50) | 7 (18.42) | ||
CD44 | 1.000 | |||
0 or +1 | 40 (38.83) | 15 (39.47) | ||
+2 or +3 | 63 (61.17) | 23 (60.53) | ||
N-cadherin | 0.072 | |||
0 | 102 (99.03) | 35 (92.11) | ||
+1 | 1 (0.97) | 2 (5.26) | ||
+2 | 0 (0.00) | 1 (2.63) | ||
Fibronectin | 0.196 | |||
0 | 6 (5.77) | 6 (15.79) | ||
+1 | 62 (59.62) | 22 (57.89) | ||
+2 | 33 (31.73) | 10 (26.32) | ||
+3 | 3 (2.88) | 0 (0.00) | ||
Vimentin | 0.268 | |||
negative | 104 (100.00) | 37 (97.37) | ||
positive | 0 (0.00) | 1 (2.63) | ||
S100A4 | 0.384 | |||
0 | 24 (23.08) | 14 (36.84) | ||
+1 | 48 (46.15) | 14 (36.84) | ||
+2 | 19 (18.27) | 7 (18.42) | ||
+3 | 13 (12.50) | 3 (7.89) |