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. 2021 Jul 2;16(7):e0254000. doi: 10.1371/journal.pone.0254000

Table 7. IHC expression of EMT-related markers vs. tumor deposits.

Tumor Deposits
Absent Present p-value
Number 104 38
E-cadherin 0.004*
+1 1 (0.96) 4 (10.53)
+2 13 (12.50) 9 (23.68)
+3 90 (86.54) 25 (65.79)
β-catenin 0.736
0 46 (44.66) 18 (47.37)
+1 33 (32.04) 9 (23.68)
+2 21 (20.39) 9 (23.68)
+3 3 (2.91) 2 (5.26)
Claudin-1 0.007*
0 4 (3.85) 8 (21.05)
+1 40 (38.46) 9 (23.68)
+2 43 (41.35) 17 (44.74)
+3 17 (16.35) 4 (10.53)
CD44 0.346
0 5 (4.85) 5 (13.16)
+1 35 (33.98) 10 (26.32)
+2 46 (44.66) 16 (42.11)
+3 17 (16.50) 7 (18.42)
CD44 1.000
0 or +1 40 (38.83) 15 (39.47)
+2 or +3 63 (61.17) 23 (60.53)
N-cadherin 0.072
0 102 (99.03) 35 (92.11)
+1 1 (0.97) 2 (5.26)
+2 0 (0.00) 1 (2.63)
Fibronectin 0.196
0 6 (5.77) 6 (15.79)
+1 62 (59.62) 22 (57.89)
+2 33 (31.73) 10 (26.32)
+3 3 (2.88) 0 (0.00)
Vimentin 0.268
negative 104 (100.00) 37 (97.37)
positive 0 (0.00) 1 (2.63)
S100A4 0.384
0 24 (23.08) 14 (36.84)
+1 48 (46.15) 14 (36.84)
+2 19 (18.27) 7 (18.42)
+3 13 (12.50) 3 (7.89)