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. 2020 Jul 1;120(15):7592–7641. doi: 10.1021/acs.chemrev.0c00215

Figure 12.

Figure 12

Wall-eyed stereo view of the interaction of the proximal inhibitor binding pocket with (S)-flurbiprofen as observed from the side (i.e., parallel to the plane of the membrane) (A) or looking upward from the membrane (B). (S)-Flurbiprofen is colored by element, and its surface is shown as a mesh. Side chains of the residues comprising the pocket are displayed, and their surface is shown in solid tan. From PDB 1EQH.