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. 2020 Jul 1;120(15):7592–7641. doi: 10.1021/acs.chemrev.0c00215

Figure 16.

Figure 16

Wall-eyed stereo view of the interaction of the central inhibitor binding pocket with indomethacin as observed from the side (i.e., parallel to the plane of the membrane) (A) or looking upward from the membrane (B). Indomethacin is colored by element, and its surface is shown as a mesh. Side chains of the residues comprising the pocket are displayed, and their surface is shown in solid tan. From PDB 4COX.