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. 2021 Jan 31;28(8):4387–4399. doi: 10.1245/s10434-020-09496-1

Table 3.

Severity of postoperative complications according to the Clavien–Dindo classification

Outcomes Overall [n = 27] Whipple/PPPD [n = 14] Total pancreatectomy [n = 13]
Overall [n = 14] Whipple/PPPD only [n = 9] Whipple/PPPD plus distal pancreatectomy [n = 5]
Clavien–Dindo grade
 I 4 (15) 2 (14) 2 (22) 0 (0) 2 (15)
 II 6 (22) 1 (7) 1 (11) 0 (0) 5 (29)
 IIIA 6 (22) 5 (36) 2 (22) 3 (60) 1 (8)
 IIIB 1 (4) 1 (7) 0 (0) 1 (20) 0 (0)
 IVA 7 (26) 4 (29) 3 (33) 1 (20) 3 (23)
 IVB 2 (7) 1 (7) 1 (11) 0 (0) 1 (8)
 V 1 (4) 0 (0) 0 (0) 0 (0) 1 (8)
Clavien–Dindo grade III or higher complications 17 (63) 11 (79) 6 (67) 5 (100) 6 (46)
Multiple Clavien–Dindo grade III or higher complications 13 (48) 9 (64) 4 (44) 5 (100) 4 (31)
Clavien–Dindo grade III 7 (26) 6 (43) 2 (22) 4 (80) 1 (8)
Clavien–Dindo grade III specified POPF (1) POPF (1) DGE (1)
POPF + anastomotic leakage (1) POPF + anastomotic leakage (1)
POPF + DGE (1) POPF + DGE (1)
POPF + bile leakage (1) POPF + bile leakage (1)
POPF + PPH + abdominal abscess + wound infection/abscess (1) POPF + PPH + abdominal abscess + wound infection/abscess (1)
Chyle leakage (1) DGE (1)
DGE (1)
Clavien–Dindo grade IV 9 (33) 5 (36) 4 (44) 1 (20) 4 (31)
Clavien–Dindo grade IV specified

PPH (4)

Respiratory insufficiency (2)

Cardiac tamponade (1)

Esophageal perforation + PPH (1)

POPF + PPH (1)

PPH (2)

Respiratory insufficiency (2)

POPF + PPH (1)

PPH (2)

Cardiac tamponade (1)

Esophageal perforation + PPH (1)

Clavien–Dindo grade V 1 (4) 0 (0) 0 (0) 0 (0) 1 (8)
CCI (median [range]) 47.8 [8.7–100] 50.6 [8.7–95.3] 35.7 [8.7–95.3] 54.8 [47.8–69.2] 32.0 [12.2–100]
CCI
 0–19 5 (19) 2 (14) 2 (22) 0 (0) 3 (23)
 20–39 7 (26) 3 (21) 3 (33) 0 (0) 4 (31)
 40–59 7 (26) 5 (36) 1 (11) 4 (80) 2 (15)
 60–79 5 (19) 3 (21) 2 (22) 1 (20) 2 (15)
 ≥ 80 3 (11) 1 (7) 1 (11) 0 (0) 2 (15)

Data are expressed as n (%) unless otherwise specified

CCI Cumulative Complication Index, DGE delayed gastric emptying, POPF postoperative pancreatic fistula, PPH post-pancreatectomy hemorrhage, PPPD pylorus-preserving pancreatoduodenectomy