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. 2021 Jul 3;345:130394. doi: 10.1016/j.snb.2021.130394

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© 2021 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 3 — In vitro detection of Ig total, IgG, IgM, and IgA in serum. (A) The vertical axis represents the ΔIROP (%) corresponding to the total Ig levels detected in the sera of patients with severe, moderate, mild, and no SARS-CoV-2 infection. (B) The vertical axis represents the ΔIROP (%) corresponding to the levels of specific IgG, IgM, and IgA antibodies in the same group of patients. Abbreviations: ΔIROP, difference in the increased relative optical power signal between the reference and after recognition of the biological event; Ig, immunoglobulin.