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. 2021 Jul 2;11:13780. doi: 10.1038/s41598-021-93175-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Distribution of antibody results. (A) 3D scatterplots representing the relation between IgG-N, IgG-S and IgM antibodies detected in three phases of the disease: Infection phase, inflammation phase and recovery phase. Values are expressed in antibody level/cutoff. (B) ROC curves for the classification tree model: Applied on the infection phase, inflammation phase and recovery phase data. The x-axis represents the fraction of negative examples classified as positives. The y-axis shows the fraction of positive examples classified as positives. The probabilities for class prediction were estimated by leave-one-out cross validations.