Table 2.

Active Clinical Trials in FRDA

Agent	Agent	Status	Disease Stage	Clinical Trial Number
Vatiquinone (MOVE-FA)	PTC 743	Phase II/III pivotal	Ambulatory Children	NCT04577352
CTI-1601	Tat-frataxin	Phase I/II	Later ambulatory, non ambulatory adults	NCT04519567
NAD+ and Exercise in FRDA (ExRx in FA)	Nicotinamide riboside	Phase II	Ambulatory, early non ambulatory adults and children	NCT04192136
RT001	Deuterated fatty acid	Phase II/III Pivotal trial	Ambulatory,early non ambulatory adults and children	NCT04102501
RTA 408 (MOXIe)	Omaveloxolone	Phase II/III Potentially Pivotal trial	Ambulatory,early non ambulatory adults and older children	NCT02255435
NAD+ precursor supplementation		Phase I/II	Later ambulatory, non ambulatory adults	NCT04817111