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. 2021 Jun 16;24:100351. doi: 10.1016/j.ensci.2021.100351

Fig. 2.

Fig. 2

The schema represents the relationships between anti-phospholipid syndrome, endothelin-1 (ET-1), and cilostazol. The endothelial cells with anti-β2GPI antibodies induce increased expression of mRNA for ET-1, leading to vasoconstriction. Cilostazol prevents ET-1-induced smooth muscle constriction.