Representative examples of AlphaFold2 on multidomain protein structures in CASP14. The experimental structures are shown in red cartoons, while the predicted models are shown in different colors for different domains. A, modeling results for T1038, where AlphaFold2 achieved excellent performance on both the domain-level and full-length models. B, modeling results for T1052, where the domain-level models achieved an extremely high accuracy, but the full-length assembled structure had incorrect domain orientations.