REAGENT or RESOURCE	SOURCE	IDENTIFIER
Bacterial and virus strains
Bacterial cells from E. coli	BACPAC Resources Center
Chemicals, peptides, and recombinant proteins
Glycerol	Sigma	G-6279
Glucose	Sigma	G8769
Tris	Sigma	T1503
EDTA	Merck	1084520250
NaOH	Merck	106462
SDS	Bio-Rad	1610302
Potassium acetate	Sigma	P1190
Isopropanol	Sigma	I9516
Ethanol	Sigma	51976
RNAse	QIAGEN	19101
Sodium acetate	Sigma	S7899
Glacial acetic acid	Sigma	A6283
Agarose	Conda	8010.22
Xylene	AnalaR NORMAPURE	28975.291
Green-dUTP	Abbott Molecular	02N32-050
Red-dUTP	Abbott Molecular	02N34-050
HCL	Fisher Chemical	10467640
PBS	Sigma	D8537
Wash Buffer	Agilent Technologies	G9401A;G9402A
Proteinase K	Dako	S3020
Vysis LSI/WCP hybridization buffer	Vysis	30-804826
VECTASHIELD Antifade Mounting Medium with DAPI	Vector Laboratories	H-1200
VECTASHIELD Antifade Mounting Medium	Vector Laboratories	H-1400
Buffer TE	Invitrogen	AM9849
Sspe 20× buffer	Gibco	15591-043
N-Lauroylsarcosine sodium salt solution	Sigma	L-7414
Sodium borohydride	Sigma	452882
BSA	Sigma	A9418
Post-Hybridization Wash Buffer	Vitro-Master diagnostica	MAD-FS0105-1
Critical commercial assays
Nick Translation Kit	Roche	10976776001
SureTag DNA Labeling Kit	Agilent Technologies	5190-3399
SureTag DNA Labeling Kit Purification Columns	Agilent Technologies	5190-3391
Dako’s Histology FISH Accessory Kit	Dako	K5799
Vysis IntelliFISH Universal FFPE Tissue Pretreatment and Wash Reagents	Vysis	08N85-005
Vysis IntelliFISH Hybridization Buffer	Vysis	08N87-001
DNeasy Blood & Tissue Kits	QIAGEN	Cat#69506
Oligo aCGH/Chip-on-chip Hybridization Kit	Agilent Technologies	5188-5220
SurePrint G3 Mouse Genome CGH Microarray Kit, 4×180K	Agilent Technologies	G4839A
SurePrint G3 Human CGH Microarray Kit, 4×180K	Agilent Technologies	G4449A
SurePrint G3 Human CGH Microarray Kit, 8×60K	Agilent Technologies	G4450A
Pretreatment Kit	Vitro-Master diagnostica	MAD-FISH-PTK
Experimental models: organisms/strains
Mouse: Mouse: MCRS1lox/lox: Mcrs1tm1.1Ndj	Dr. Nabil Djouder, (Fawal et al., 2015) Spanish National Cancer Research Center (CNIO)	J:232965
Mouse: mTORlox/lox: B6.129S4-Mtor tm1.2Koz/J	(Risson et al., 2009)	J:011009
Mouse: p53 lox/lox: B6.129P2-Trp53tm1Brn/J	(Marino et al., 2000)	J:61961
Mouse: Villin-CreERT2 : Tg(Vil-cre/ERT2)23Syr	(el Marjou et al., 2004)	J:92295
Software and algorithms
CytoVision	Leica Microsystems	N/A
Other
Mouse Cot-1 DNA	Invitrogen	Cat#18440-016
Human Cot-1 DNA	Invitrogen	Cat#15279-011
Positively charged glass slides	Menzel-Glaser	N/A
ThermoBrite instrument	Leica	N/A
Leica DM5500B fluorescence microscope	Leica	N/A
Rubber cement	Marabu	29010010000
25×50 mm Cover slips	Menzel-Glaser	15747592