Table 3.
Level | Parameter | Group | ||
---|---|---|---|---|
Control | Empagliflozin | |||
Apical level | Systolic | LVESA [mm2] | 47.5 ± 4.3*** | 54.4 ± 5.1*** |
LVIDs [mm] | 7.1 ± 0.4*** | 7.9 ± 0.5*** | ||
Diastolic | LVEDA [mm2] | 69.3 ± 4.4*** | 74.3 ± 5.3*** | |
LVIDd [mm] | 8.8 ± 0.4*** | 9.3 ± 0.4*** | ||
Function | FS [%] | 19.1 ± 3.3** | 15.1 ± 4.0** | |
FAC [%] | 33.6 ± 3.0*** | 27.2 ± 3.5*** | ||
EF [%] | 42.9 ± 5.4** | 34.9 ± 6.4** | ||
Papillary muscles level | Systolic | LVESA [mm2] | 47.1 ± 3.4*** | 52.4 ± 4.0*** |
LVIDs [mm] | 7.8 ± 0.4*** | 7.5 ± 0.5*** | ||
Diastolic | LVEDA [mm2] | 78.4 ± 3.8*** | 80.2 ± 4.5*** | |
LVIDd [mm] | 9.5 ± 0.2*** | 9.3 ± 0.3*** # | ||
Function | FS [%] | 17.8 ± 2.7*** | 20.1 ± 3.2** | |
FAC [%] | 39.3 ± 2.9*** | 35.7 ± 3.4** | ||
EF [%] | 40.2 ± 4.6*** | 45.4 ± 5.4** |
Abbs. as in Table 2. ** P < 0.01 vs. baseline and *** P < 0.001 vs. baseline, # P < 0.05 vs. damage group