Table 4.

Physical and 2DE structural and functional parameters at 4 weeks (final)

	Level	Parameter	Group
			Control	Empagliflozin
		Body weight [gr]	398 ± 46	382 ± 21
Apical level	Systolic	LVESA [mm2]	52.4 ± 5.4***	53.5 ± 5.1***
		LVIDs [mm]	7.9 ± 0.5***	7.8 ± 0.5***
	Diastolic	LVEDA [mm2]	69.3 ± 5.6**	77.1 ± 5.3***
		LVIDd [mm]	9.5 ± 0.5**	9.0 ± 0.4*
	Function	FS [%]	17.6 ± 4.2**	13.7 ± 4.0**
		FAC [%]	27.6 ± 3.8***	31.0 ± 3.5***
		EF [%]	37.3 ± 6.8**	32.3 ± 6.4**
Papillary muscles level	Systolic	LVESA [mm2]	60.6 ± 4.4***	57.5 ± 4.0***
		LVIDs [mm]	8.1 ± 0.5***	8.2 ± 0.5***
	Diastolic	LVEDA [mm2]	89.2 ± 4.8**	85.3 ± 4.5***
		LVIDd [mm]	9.8 ± 0.3***	9.8 ± 0.3***
	Function	FS [%]	18.6 ± 3.4***	17.6 ± 3.2***
		FAC [%]	34.1 ± 3.7**	33.5 ± 3.4**
		EF [%]	40.1 ± 5.8***	39.4 ± 5.4**

Abbs. as in Table 2. * P < 0.05 vs. baseline, ** P < 0.01 vs. baseline and *** P < 0.001 vs. baseline