Table 1.
Summary of primary sources of IPD
| Study | N | Study type | Inclusion criteria | Length of follow-up | Follow-up points | Mean age (SD) | Gender (% female) | RCT intervention | Duration of RCT intervention |
|---|---|---|---|---|---|---|---|---|---|
| CASPER Plus | 485 (358 at 12 m) | RCT | 65 years or older with depression | 18 months | 0, 4, 12 and 18 months |
Intervention group: 71.9 (6.03) Control: 71.6 (5.96) |
Intervention group: 59.1 Control: 63.1 |
Collaborative care | 8–10 weeks |
| REEACT | 461 | RCT | Adults with depression | 24 months | 0, 4, 12 and 24 months | 39.86 (12.65) | 67 | cCBT | 6 weeks |
| REEACT 2 | 369 | RCT | Adults with depression | 12 months. | 0, 4 and 12 months | 40.6 (13.8) | 64.5 | cCBT | 4 months |
| COINCIDE | 387 | RCT | Adults with depression and multi-morbidity | 24 months | 0, 4, 12, 24 | 58.5 (11.7) | 38 | Collaborative care | 3 months |
| COBRA | 440 | RCT | Adults with depression | 18 months | 0, 6, 12, 18 | 43.5 (14.1) | 66 | Behavioural activation vs CBT | 16 weeks |
| CADET | 581 | RCT | Adults with depression | 12 months | 0, 4,12 | 44.4 (13.3) | 71.9 | Collaborative care | 14 weeks |
| Healthlines Depression | 609 | RCT | Adults with depression | 12 months | 0, 4,8,12 |
Intervention group: 49.1 (12.9) Control: 50 (12.8) |
Intervention group: 69 Control: 68 |
Complex intervention (integrated telehealth) | 12 months |
| WYLOW | 439 | Longitudinal observational cohort study | Adults with depression | 12 months (Start-point = Remission) | Monthly | 41.28 (14.59) | 59.7 | None (cohort are followed-up after LiCBT) | NA |