Table 5.

Application of the LR, Fieller’s and delta methods to the MCTFR data for the SNPs associated with at least two traits at the 1 × 10⁻³ significance level

		Allele			P value				95% CI
SNP	Position	Minor	Major	MAF	HWE test	Levene’s test	Traits	$\widehat{\gamma }$	LR	Fieller	Delta
rs792959	67,891,800	G	A	0.210	0.891	7.315 × 10−4	DRG	2	(1.0294, 2]	(1.0293, 2]	[0, 2]
rs792959	67,891,800	G	A	0.210	0.891	7.945 × 10−5	BD	2	(1.0306, 2]	(1.0304, 2]	[0, 2]
rs4825722	119,728,451	A	G	0.164	0.458	6.695 × 10−4	DEP	1.0048	(0.2423, 2]	(0.2423, 2]	[0, 2]
rs4825722	119,728,451	A	G	0.164	0.458	8.157 × 10−5	BD	0.8540	[0, 2]	[0, 2]	[0, 2]
rs4825726	119,760,628	A	G	0.219	0.074	1.856 × 10−4	DEP	0.8474	(0.1382, 2]	(0.1381, 2]	[0, 1.8975)
rs4825726	119,760,628	A	G	0.219	0.074	1.411 × 10−5	BD	1.2677	(0.2400, 2]	(0.2397, 2]	[0, 2]
rs17261621	119,761,122	A	C	0.123	0.599	2.879 × 10−6	DRG	0.2851	[0, 1.2309)	[0, 1.2315)	[0, 0.6682)
rs17261621	119,761,122	A	C	0.123	0.599	2.310 × 10−5	BD	0.4834	(0.0028, 2]	(0.0025, 2]	[0, 1.1449)
rs2196260	119,761,909	G	A	0.215	0.070	5.501 × 10−5	DEP	0.7413	(0.0839, 2]	(0.0836, 2]	[0,1.6696)
rs2196260	119,761,909	G	A	0.215	0.070	2.486 × 10−5	BD	1.3667	(0.2527, 2]	(0.2523, 2]	[0, 2]