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. 2021 Jul 2;21:636. doi: 10.1186/s12879-021-06243-z

Table 1.

MDRGN, ESBL, and CRGN associated BSIs frequency among most common gram-negative bacteria as well as MRSA and MRCoNS among gram-positive associated BSIs during 2015–2019

2015
n (%)
2016
n (%)
2017
n (%)
2018
n (%)
2019
n (%)
p-value
MDR 20 (40) 36 (50) 53 (49.5) 66 (53.75) 29 (46.8) 0.588
E. coli 12 (60) 22 (61.1) 26 (49.1) 13 (19.7) 18 (62.1)
K. pneumoniae 3 (15) 3 (8.3) 4 (7.5) 9 (13.6) 5 (17.2)
Acinetobacter spp. 2 (10) 3 (8.3) 2 (3.8) 0 (0) 0 (0)
Pseudomonas spp. 1 (5) 6 (16.7) 18 (34) 43 (65.2) 6 (20.7)
ESBL 5 (15.2) 31 (46.3) * 43 (43) * 66 (55.5) 28 (45.9) 0.002
E. coli 5 (100) 18 (75) 20 (60.6) 14 (82.4) 13 (50)
K. pneumoniae 0 (0) 3 (15) 4 (16) 7 (33.3) 6 (31.6)
Acinetobacter spp. 0 (0) 2 (100) 3 (100) 0 (0) 0 (0)
Pseudomonas spp. 0 (0) 6 (100) 15 (88.2) 45 (97.8) 9 (100)
CRGN 15 (14.9) 17 (16.8) 23 (22.8) 42 (41.6) 4 (4) < 0.0001
E. coli 11 (84.6) 11 (40.7) 5 (13.9) 3 (14.3) 0 (0)
K. pneumoniae 2 (66.7) 2 (40) 0 (0) 1 (7.1) 0 (0)
Acinetobacter spp. 1 (33.3) 3 (100) 3 (100) 0 (0) 0 (0)
Pseudomonas spp. 0 (0) 1 (16.7) 15 (75) 38 (82.6) 4 (44.4)
MRSA 0 (0) 3 (50) 1 (25) 0 (0) 0 (0) 0.038
MR-CONS 13 (86.7) 7 (53.8) 13 (92.9) 22 (78.6) 5 (62.5) 0.112

MDRGN: multidrug-resistant gram-negative bacteria; ESBL: extended-spectrum beta-lactamases (ESBL)-producing gram-negative bacteria; CRE: carbapenem-resistant Enterobacterales; CRGN: carbapenem-resistant gram-negative bacteria; MRCONS: methicillin-resistant coagulase-negative Staphylococci; MRSA: methicillin-resistant Staphylococcus aureus. P-values marked with bold indicate statistically significant p-values