Table 3.
Univariate logistic regression analysis of variables investigated for prediction of MDR gram-negative infection in cancer patients with bloodstream infection
| Non-MDR (n = 19,50.4%) | MDR (n = 188, 49.6%) | OR (95% CI) | p-value | |
|---|---|---|---|---|
| Sex | ||||
| Female | 78 (40.8) | 95 (50.5) | 1.48 (0.986, 2.221) | 0.059 |
| Male* | 113 (59.2) | 93 (49.5) | ||
| Age | ||||
| < 60 | 125 (65.4) | 136 (72.3) | 1.381 (0.892,2.138) | 0.148 |
| > 60* | 66 (34.6) | 52 (27.7) | ||
| Malignancy | ||||
| Solid organ tumor | 84 (44) | 83 (44.1) | 1.007 (0.671,1.511) | 0.973 |
| Hematologic malignancy* | 107 (56) | 105 (55.9) | ||
| ESR | 67.96 (34.76) | 75.40 (37.68) | 1.006 (0.999,1.013) | 0.101 |
| CRP | 78.60 (37.28) | 88.05 (43.48) | 1.006 (1.000,1.012) | 0.065 |
| WBC count | ||||
| < 4000/μl | 97 (51.3) | 122 (64.9) | 1.753 (1.159,2.651) | 0.008 |
| > 4000/μl* | 92 (48.7) | 66 (35.1) | ||
| Neutropenia | ||||
| Yes (< 1500/μl) | 69 (36.7) | 86 (46.2) | 1.483 (0.981,2.243) | 0.062 |
| No (> 1500/μl) * | 119 (63.3) | 100 (53.8) | ||
| Febrile neutropenia | ||||
| No* | 47 (24.6) | 59 (31.4) | 1.401 (0.893,2.200) | 0.142 |
| Yes | 144 (75.4) | 129 (68.6) | ||
| Year | ||||
| 2015 | 24 (12.6) | 18 (9.6) | 0.960 (0.429,2.146) | 0.921 |
| 2016 | 32 (16.8) | 31 (16.5) | 1.240 (0.604,2.546) | 0.558 |
| 2017 | 51 (26.7) | 52 (27.7) | 1.305 (0.681,2.501) | 0.422 |
| 2018 | 52 (27.2) | 62 (33) | 1.526 (0.805,2.894) | 0.195 |
| 2019* | 32 (16.8) | 25 (13.3) | ||
| Enterobacterales | ||||
| No ** | 44 (81.5) | 110 (58.8) | 3.120 (1.481,6.575) | 0.003 |
| Yes* | 10 (18.5) | 78 (41.5) | ||
* Reference
** non-fermenter gram-negative BSI. P-values marked with bold indicate statistically significant p-values