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. 2021 Jul 2;21:186. doi: 10.1186/s12906-021-03362-7

Table 2.

Anticancer effects of samples against A-375 and MDA-MB-468

Samples A-375 MDA-MB-468
LCL* IC50* UCL* LCL IC50 UCL
limonene 176.18 246.05 343.62 1636.44 2118.94 2743.71
LimChiNPsa 13.53 30.24 67.58 498.29 650.70 849.72
CAEOb 4832.01 10,564.00 23,095.00 781.41 2037.53 5312.86
CAChiNPsc 15.66 55.00 193.16 144.20 240.44 400.92
CLEOd 0.49 10.54 228.46 57.41 137.03 327.06
CLChiNPse 3.270 0.124 0.05 10.41 40.32 156.14
CSEOf 0.01 0.02 0.03 139.97 168.00 201.65
CSChiNPsg 0.02 0.03 0.05 2.74 23.65 204.43

a chitosan nanoparticles containing limonene, b C. aurantium EO, c chitosan nanoparticles containing C. aurantium EO, d C. limon EO, e chitosan nanoparticles containing C. limon EO, f C. sinensis EO, chitosan nanoparticles C. sinensis EO

* The half-maximal inhibitory concentration or IC50 (μg/mL) with lower and upper confidence limits; LCL and UCL