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. 2021 Jun 28;13:5063–5075. doi: 10.2147/CMAR.S308986

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© 2021 Zhang et al.

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Identification of potential miRNA-mRNA pairs in the setting of Myc: (A) Constructed a significant miRNA-mRNA pair in HCC: blue=down- regulated, red =up-regulated. (B) The TargetScan predicted website, the target combination site between the SLC6A1 3ʹUTR and miR-212-3p/miR-217, was shown, respectively. (C) The correlation analysis between Myc and miR-212-3p/SLC6A1 axis expression in HCC tissues from TCGA data. (D-E). The expression distribution of SLC6A1 in 365 HCC tissues, compared with 50 adjacent normal liver tissues from the TCGA databases. (F) Expression of SLC6A1 in HCC and normal tissue samples from the TCGA and GTEx databases. (G) Kaplan–Meier analysis of HCC according to SLC6A1 expression.