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. 2021 Jun 29;14:2989–3000. doi: 10.2147/IJGM.S317350

Table 4.

Comparison of Laboratory Findings in Patient Groups Classified According to the Disease Severity (Mild, Moderate, and Severe)

Mild Severe Critical
Median IQR (25-75) Median IQR (25-75) Median IQR (25-75) p*
Hematological Parameters
WBC (10^3/uL) 6.70 5.25–8.43 6.27 5.02–7.90 6.88 5.82–10.06 0.035
Hemoglobin (g/dL) 13.8 12.50–15.10 13.60 12.50–14.60 12.80 11.50–13.80 0.002
Neutrophil (10^3/uL) 3.76 2.63–5.09 4.06 2.87–5.58 4.72 3.72–7.36 0.004
Lymphocyte (10^3/uL) 2.00 1.48–2.74 1.51 1.08–1.97 1.08 0.72–1.23 < 0.001
Thrombocyte (10^3/uL) 216.00 184.50–264.00 205.00 173.00–258.25 179.00 141.50–246.50 0.013
Biochemical Parameters
CRP (mg/L) 8.50 3.95–19.80 42.00 17.00–83.00 136.00 107.70–199.00 < 0.001
Procalcitonin (µg/L) 0.03 0.02–0.05 0.04 0.03–0.08 0.305 0.15–1.55 < 0.001
Lactate dehydrogenase (U/L) 218.50 177.00–259.00 274.00 217.00–341.00 357.00 267.00–480.00 < 0.001
Creatinine (mg/dL) 0.76 0.62–0.88 0.84 0.68–0.99 1.02 0.86–1.78 < 0.001
Albumin (g/L) 43.00 40.00–45.00 36.00 33.00–38.00 31.00 26.00–35.00 < 0.001
D-dimer (µg/L) 500.00 270.00–880.00 740.00 470.00–1065.00 1120.00 750.00–3220.00 < 0.001
Ferritin (µg/L) 86.85 39.07–183.55 184.00 99.00–333.50 247.00 112.00–541.00 < 0.001
Troponin (pg/mL) 2.70 1.45–4.00 3.70 2.15–5.52 6.40 3.60–22.85 < 0.001
Fibrinogen (mg/dL) 382.00 280.00–559.00 500.00 421.00–583.00 562.00 405.00–643.00 0.001
NLR 1.80 1.30–2.79 2.74 1.66–4.26 5.73 3.59–9.37 < 0.001
CRP/Abumin Ratio 0.20 0.08–0.71 1.29 0.48–2.68 4.86 3.22–6.04 < 0.001

Note: Data are expressed as median and interquartile range (IQR). *Kruskal–Wallis test was used to assess numerical data of patients grouped according to disease severity (eg, mild, severe, or critical).

Abbreviations: WBC, white blood cell; NLR, neutrophil–lymphocyte ratio; CRP, C-reactive protein.