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. 2021 Jul 2;15(4):041501. doi: 10.1063/5.0058732

TABLE III.

Recent advances of elasto-inertial contraction–expansion microfluidics.

Targets Applications Sample flow rate Performance Reference
6 μm beads Three-dimensional single-stream particle focusing 300 μl/h Focusing efficiency:>99% 101
3.2/4.8/13 μm particles Three-dimensional single-stream particle focusing 60 μl/min 4.8 μm particles have the best focusing performance 27
Plasma Plasma extraction in the diluted blood sample 50 μl/min Plasma purity: 99.93% (the first filtration) 99.99% (the second filtration) 102
Jurkat cells Separation of Jurkat cells and yeast cells 20 μl/min Recovery rate: 99.6%
Purity: 24%
Enrichment ratio: 11.9%
104
H1299 cells Separation of H1299 cells from the blood cells 500 μl/h Separation efficiency: 98% 105
NCI-H1299 cells / Blood cells Separation of tumor cells from the blood cells 10 μl/min Separation efficiency: 100% (NCI-H1299 cells) >90% (blood cells) 106
2/10 μm particles Size-based particle separation ∼1 μl/min Achieving complete particle separation 107