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. 2021 Jul 3;12(7):670. doi: 10.1038/s41419-021-03943-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Expression of AC0733521.1 in the normal breast epithelium cell line (MCF-10A) and BC cell lines was detected by qRT-PCR and normalized to β-actin. b, c qRT-PCR analysis of AC073352.1 expression in control, siAC073352.-1-, siAC073352.-2-, siAC073352.-3-, and pcDNA-AC073352.1-treated BC cells. d, f Transwell assays were used to investigate the changes in the migratory and invasive capabilities of MDA-MB-468 and MCF-7 cells after transfection with siAC073352.1s. e, g Transwell assays were used to investigate the changes in the migratory and invasive capabilities of MDA-MB-231 and BT549 cells after transfection with pcDNA-AC073352.1. h, i Wound healing assay assessing BC cells’ metastasis. The data represent the mean ± SEM from three independent experiments. Values are expressed as mean ± SEM, n = 3. *p < 0.05, **p < 0.01, ***p < 0.001, and ns not significant.