Table 2.
Associations between factors of cortical change and APOE status, and changes in cognitive domains.
| Global | Fronto-temporal factor | Occipito-parietal factor | |
|---|---|---|---|
| APOE e4 carrier | −0.100 (0.038) | −0.044 (0.414) | 0.012 (0.774) |
| g | 0.431 (<0.001) | −0.024 (0.738) | −0.072 (0.212) |
| Visuospatial | 0.415 (0.002) | −0.139 (0.286) | −0.143 (0.229) |
| Processing speed | 0.369 (<0.001) | −0.010 (0.893) | −0.066 (0.256) |
| Memory | 0.363 (<0.001) | 0.066 (0.352) | −0.026 (0.644) |
Standardised estimates (p values) are reported for associations between the three factors of cortical volumetric change (global, fronto-temporal and posterior-parietal), APOE status (where 1 = at least 1 × e4 allele), and the three cognitive domains (visuospatial, processing speed and memory). Bold typeface denotes FDR-q < 0.05.