Fig. 2.

Elderly with Aβ deposition display cognitive deficits. a–l Cognitive scores and estimated slopes reflecting the person-specific rate of cognitive decline within a mean follow-up period of 5.7 ± 3.6 years (interquartile range: 3–9 years). c–d Elderly individuals with Aβ deposition display deficits in perceptual speed and a faster rate of cognitive decline in this domain, t (28) = 2.68, p = 0.012 and t (26) = 2.15, p = 0.04, respectively. a–b and e–l Global cognition, working memory, episodic memory, semantic memory, and visuospatial ability did not differ between elder individuals with or without Aβ deposition. Data are displayed in boxplots where the median is represented by the horizontal line and the whiskers represent the 25th and 75th percentiles; a, c–f, and h–l two-tailed Student t test; b, g two-tailed Mann–Whitney test; Aβ−, n = 14; Aβ+, n = 16; g global. Full circles represent outliers. ^*p < 0.05