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. 2021 Jul 3;21:141. doi: 10.1186/s12902-021-00787-6

Table 1.

Primary Malignancy Sites in patients Admitted to Hospital with a Diagnosis of a Secondary Adrenal Malignancy

Primary Site
(ICD10 AM codes)
Total N
N = 15,040
Adrenal Insufficiency
N = 172*
Adrenal Crisis
N = 24
N (%) N (%) N (%)
Malignant neoplasms of respiratory and intrathoracic organs (C30-C39) 7450 (49.5) 53 (30.8) 4 (16.7)
Malignant neoplasms of digestive organs (C15-C26) 2409 (16.0) 20 (11.6) 0
Melanoma and other malignant neoplasms of skin (C43-C44) 1392 (9.3) 28 (16.3) 3 (12.5)
Malignant neoplasms of urinary tract (C64-C68) 1196 (8.0) 27 (15.7) 2 (8.3)
Malignant neoplasms of ill-defined, secondary and unspecified sites (C76-C80) 916 (6.1) 12 (7.0) 8 (33.3)
Malignant neoplasm of breast (C50) 688 (4.6) 18 (10.5) 1 (4.2)
Malignant neoplasms of male genital organs (C60-C63) 305 (2.0) 4 (2.3) 3 (12.5)
Malignant neoplasms of female genital organs (C51-C58) 211 (1.4) 1 (0.6) 0
Malignant neoplasms of mesothelial and soft tissues (C45-C49) 112 (0.7) 0 0
Malignant neoplasms of lip, oral cavity and pharynx (C00-C14) 92 (0.6) 1 (0.6) 1 (4.2)
Benign neoplasms (D10-D36) 65 (0.4) 3 (1.7) 1 (4.2)
Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue (C81-C96) 55 (0.4) 0 0

Malignant neoplasms of thyroid and other endocrine glands

(C73-C75)

38 (0.3) 1 (0.6) 0
Malignant neoplasms of eye, brain, and other parts of central nervous system (C69-C72) 38 (0.3) 0 0
Malignant neoplasms of bone and articular cartilage (C40-C41) 34 (0.2) 1 (0.6) 0
Neoplasms of uncertain or unknown behaviour (D37-D48) 31 (0.3) 3 (1.7) 1 (4.2)
In situ neoplasms (D00-D09) 8 (0.1) 0 0

* Total reflects more than one primary site in some patients