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. 2021 Jul 3;22:39. doi: 10.1186/s40360-021-00507-9

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Cross sections in liver of rats showed the effect of Melittin on liver tissues in post isoniazid and rifampicin-induced hepatotoxicity. (a): Normal control (NC); (b): toxic group (T); (c): treated group 15 μg Melittin; (d): treated group 30 μg Melittin (Mel 30); (e): Normal recovery group (NR). (a): Normal group (N), 200x; (b & c): Toxic group (T), 200x; (d & e): Toxic group(T) 400x; (f): Mel 15 mg, 200x; (g): Mel 30 mg, 200x; (h): Normal recovery group (NR) 200x. Histological abbreviations: Amyloids (A), Congested blood vessel (C), Ballooned hepatocytes (BH), Inflammation (I), Necrosis (N), Vasodilation (V), Fibrosis (F), Hemorrhage (H), Steatosis (ST), Hepatocytes (HC), Central vein (CV), Sinusoid (S) and Hemosiderin-laden macrophages (HS)