Table 3.

Complete blood count in male rats that received melittin post isoniazid and rifampicin-induced hepatotoxicity

	NC	T	Mel 15	Mel 30	NR
WBCs(×103/μl)	8.75 ± 1.19	5.45 ± 2.09	11.91 ± 1.32b****	14.13 ± 2.78b****	9.525 ± 2.00b*
LYM (%)	70.12 ± 7.82	79.23 ± 7.44	75.77 ± 4.19	70.52 ± 9.36	67.67 ± 11.65
MON (%)	4.55 ± 2.20	4.433 ± 2.12	7.117 ± 2.38	5.1 ± 2.18	5.75 ± 1.86
NEU (%)	19.5 ± 4.33	5.633 ± 1.09a**	13.73 ± 2.24	21.17 ± 8.98b**	22.85 ± 9.88b***
EOS (%)	1.15 ± 0.23	1.22 ± 0.26	3.23 ± 1.55b*	3.48 ± 1.43b*	3.65 ± 1.36b**
BAS (%)	0.08 ± 0.04	9.483 ± 4.41a****	0.15 ± 0.05b****	0.1 ± 0.0b****	0.08 ± 0.04b****
RBCs) × 106/μl)	9.033 ± 0.852	7.755 ± 0.26 a**	7.90 ± 0.22	7.952 ± 0.69	7.305 ± 0.34
Hb (g/dl)	15.18 ± 0.80	13.03 ± 0.89a**	14.88 ± 0.32b**	15.17 ± 0.74b**	14.5 ± 1.17b*
Hct (%)	48.78 ± 2.67	40.67 ± 2.28a***	48.22 ± 1.90b**	49.17 ± 2.47b***	47.6 ± 4.46b**
MCV (ƒL)	65.3 ± 3.31	52.4 ± 1.69a****	61.03 ± 2.11b**	62.12 ± 3.81b***	65.23 ± 5.48b****
MCH (pg)	20.32 ± 0.79	17.52 ± 0.65a***	18.85 ± 0.35	19.12 ± 1.15b*	19.85 ± 1.27b**
MCHC (g/dL)	31.13 ± 0.41	33.37 ± 0.38a****	30.90 ± 0.99b****	30.83 ± 0.36b****	30.5 ± 0.97b****
PLT (×103/μl)	777 ± 68.9	427.5 ± 146.5a**	827.8 ± 76.3b***	794.5 ± 130.6b**	607.7 ± 246.4
RDW-CV (%)	18.22 ± 2.1	24.35 ± 2.1a****	27.1 ± 1.84	28.65 ± 1.93b**	24.75 ± 1.56

Results are expressed as mean ± SD (n = 6)

WBCs White Blood Cells; Lym lymphocytes; Mon: Monocytes; Neu Neutrophils; EOS Eosinophils; Bas Basophils; RBCs Red Blood Cells; Hb Hemoglobin; Hct Hematocrit; MCV Mean corpuscular volume; MCH Mean Corpuscular Hemoglobin; MCHC Mean corpuscular Hemoglobin concentration; PLT platelets; RDW-CV Red blood cell distribution width - Coefficient of Variation

NC control, T Toxic, Mel15 Melittin15μg, Mel 30 Melittin30μg, NR Normal recovery

^*P < 0.05; ^**P < 0.01; ^***P < 0.001; ^****P < 0.0001. a: significant Vs NC group, b: significant Vs T group