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. 2021 Jun 29;37:100956. doi: 10.1016/j.eclinm.2021.100956

Table 7.

Linear regression between pH ≤ 7.28 and pH > 728 and the six dependent variables of cardiac function adjusted by propensity score matching.

pH ≤ 7.28 Md (IQR) pH > 7.28 Md (IQR) Difference in mean (pH > 7.28 vs. pH ≤ 7.28, 95% CI) P- value corrected
N (%) 135 (49.1) 140 (50.9)
Cardiac index (L/min/m2) 2.91 (2.18–4.08) 3.27 (2.52–4.07) 0.13 (−0.20–0.47) 0.115
Stroke volume index (mL/m2) 36 (25–73) 69 (43–122) 33 (21–45) < 0.001
Global ejection fraction (%) 22.6 (14.2–37.1) 36.4 (24.1–73.8) 18.3 (10.5–26.0) < 0.001
dPmax (mmHg/s) 1397 (922–1863) 1116 (783–1465) −331 (−510– −153) 0.003
Cardiac function index (L/min) 4.0 (3.0–5.8) 5.0 (3.6–6.3) 0.7 (0.2–1.3) 0.024
Cardiac power index (W/m2) 0.47 (0.30–0.62) 0.54 (0.42–0.72) 0.09 (0.03–0.15) 0.002

The significant difference in means (values for the category pH > 7.28 minus those in category pH ≤ 7.28) for the five measures of cardiac function measures are: Stroke volume index 33 (95% CI 21 to 45) mL/m2 (p < 0.001); Global ejection fraction 18.3(95% CI 10.5 to 26.0% (p < 0.001); dPmax −331 (95% CI −510 to −153) mmHg/s (p = 0.003); Cardiac function index 0.7 (95% CI 0.2 to 1.3) L/min (p = 0.024); Cardiac power index 0,09 (95% CI 0.03 to 0.15) W/m2 (p = 0.002); Cardiac index (0.13; 95% CI −0.20 to 0.47 L/min/m2; p = 0.12) was not significantly different between pH categories.