Table 2.
Statistical analyses of the relation between demographic data and PBS findings to clinical course of the disease
| Outcome N (%) |
Severity N (%) |
Intubation N (%) |
ICU admission N (%) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Discharge | Death | p-value | Non-severe | Severe | p-value | No | Yes | p-value | No | Yes | p-value | |
|
Age (years) Median (IQR) |
65 (49–75) | 74 (68–80) | 0.02 | 65 (47.5–75) | 73 (63.5–80) | 0.02 | 65 (47.5–75) | 73 (63.5–80) | 0.02 | 70 (51–77) | 71 (60–79) | 0.3 |
| Sex | ||||||||||||
| Male | 36 (66.7) | 18 (33.3) | 0.2* | 32 (59.3) | 22 (40.7) | 0.2* | 32 (59.3) | 22 (40.7) | 0.2* | 43 (79.6) | 11 (20.4) | 0.9* |
| Female | 27 (77.1) | 8 (22.9) | 25 (71.4) | 10 (28.6) | 25 (71.4) | 10 (28.6) | 28 (80) | 7 (20) | ||||
| PBS findings | ||||||||||||
| Smudge cell | 42 (66.7) | 18 (69.2) | 0.8* | 39 (68.4) | 21 (65.6) | 0.7* | 39 (68.4) | 21 (65.6) | 0.7* | 49 (69) | 11 (61.1) | 0.5* |
| Giant platelet | 27 (42.9) | 11 (42.3) | 0.9* | 24 (42.1) | 14 (43.8) | 0.8* | 24 (42.1) | 14 (43.8) | 0.8* | 30 (42.3) | 8 (44.4) | 0.8* |
| Atypical lymphocyte | 24 (38.1) | 8 (30.8) | 0.5* | 22 (38.6) | 10 (31.3) | 0.4* | 22 (38.6) | 10 (31.3) | 0.4* | 25 (35.2) | 7 (38.9) | 0.7* |
| Schistocyte | 17 (27) | 7 (26.9) | 0.9* | 15 (26.3) | 9 (28.1) | 0.8* | 15 (26.3) | 9 (28.1) | 0.8* | 19 (26.8) | 5 (27.8) | 0.9* |
| Immature neutrophil | 7 (11.1) | 6 (23.1) | 0.1* | 7 (12.3) | 6 (18.8) | 0.4* | 7 (12.3) | 6 (18.8) | 0.4* | 10 (14.1) | 3 (16.7) | 0.7** |
| Leukoerythroblastic reaction | 4 (6.3) | 4 (15.4) | 0.2** | 3 (5.3) | 5 (15.6) | 0.1** | 3 (5.3) | 5 (15.6) | 0.1** | 5 (7) | 3 (16.7) | 0.2** |
| LGL*** | 6 (9.5%) | 2 (7.7%) | 1.0 ** | 6 (10.5%) | 2 (6%) | 0.7 ** | 6 (10.5 %) | 2 (6.3%) | 0.7** | 7 (9.9%) | 1 (5.6 %) | 1.0 ** |
*Chi-square
**Fisher exact
***Large granular lymphocyte
Others: Mann-Whitney