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. 2021 Jul 5;41(11):2674–2683. doi: 10.1038/s41372-021-01136-0

Table 2.

Characteristics of 250 mothers with peripartum positive SARS-CoV-2 testing and 255 infants born 3/1/20 to 7/31/20 in Massachusetts.

Participating Hospitals, n (%)
Baystate Medical Center 20 7.8
Beth Israel Deaconess Medical Center 31 12.2
Beverley Hospital 11 4.3
Boston Medical Center 46 18.0
Brigham and Women’s Hospital 44 17.3
Cambridge Health Alliance 16 6.3
Mass General Hospital 48 18.8
Newton Wellesley Hospital 6 2.4
Tufts Medical Center 5 2.0
UMass Memorial Medical Center 23 9.0
Winchester Hospital 5 2.0
Total 255 100%
Month of birth, n (%)
  March 17 6.7
  April 79 31.0
  May 88 34.5
  June 55 21.6
  July 16 6.3
Maternal demographics
 Age, mean (SD) 30.4 6.3
Race/ethnicity, n (%)
  Hispanic (any race) 123 48.2
  Non-Hispanic White 50 19.6
  Non-Hispanic Black 48 18.8
  Non-Hispanic Asian 14 5.5
  Non-Hispanic Other 19 7.5
Maternal language, n (%)
  English 136 53.3
  Spanish 84 32.9
  Portuguese 12 4.7
  Other 23 9.0
Social vulnerability indexa themes; percentile ranking, mean (SD)
  Socioeconomic status 65.8 23.3
  Household composition 53.3 29.4
  Minority and language status 71.6 25.6
  Housing and transportation 71.5 22.0
  Overall 70.2 23.8
 Social vulnerability index overall >90th percentile, n (%) 68 26.7
Severity of maternal illness, n (%)
  Asymptomatic 174 68.2
  Symptomatic 81 31.8
  Sick at home before admission 57 70.4
  Required hospitalization for treatment of COVID-19 24 29.6
 Multiple gestation, n (%) 10 3.9
Disposition, n (%)
  Home 253 99.2
  Transfer 2 0.01
  Deaths 0 0
Infant characteristics
 Liveborn, n (%) 255 100.0
 Gestational age, weeks, mean (SD) 37.9 2.6
 Birthweight, grams, mean (SD) 3116.3 655.6
 Female sex, n (%) 131 51.4
Disposition
  Home 247 96.9
  Transfer 7 2.8
  Died 1 0.4
 Any SARS-CoV-2 test during the newborn hospitalization, n (%) 225 88.2
  Any positive newborn test (among tested) 5 2.2
 Any SARS-CoV-2 test during the 30 days post-dischargeb, n (%) 7 4.6
  Any positive newborn test (among tested) 1 14.3
Positive SARS-CoV-2 test during the hospitalization or 30 days post-dischargeb
  Any positive newborn test (overall) 6 2.4
  Any positive newborn test (among tested) 6 2.7
Main Outcomes
Mode of delivery, n (%)
  Vaginal 142 55.7
  Cesarean birth 113 44.3
 Preterm (<37 weeks), n (%) 53 20.8
  Spontaneous or augmented following initiation of labor 15 28.3
  Medically-indicated 38 71.7
Location of care, n (%)
  Any rooming-in 167 65.5
  Complete separation during entire hospital course 88 34.5
 Any direct breastfeeding during the hospitalization 152 59.6

aSocial vulnerability index uses 15 US census variables derived from zip codes and was derived by the Centers of Disease Control.

bAmong 151 infants with 1 or more encounter.