Table 1.

Use of albendazole and mebendazole for treatment of intestinal helminth infections (nematodes and cestodes)

Drug	Disease	Regimen	Cure rate (%)	Egg reduction rate (%)	References
Albendazole	Ascariasis	400 mg singlea	81.8–100	87.0–100	[8,10,42,44]
		200 mg single	92.3	98.3	[8]
	Hookworm infections	400 mg singlea	72.0–96.0	64.0–100	[8,10,42]
	Trichuriasis	400 mg singlea	27.2–81.0	0–99.0	[8,10,44]
		400 mg/day×3 days	53.0	81.0–100	[10]
	Strongyloidiasis	400 mg singlea	69.0	NA	[10]
		400 mg b.i.d.×3 days	62.0–100	NA	[10,14]
	Enterobiasis	400 mg singlea	98.1–100	NA	[13,62]
		100–400 mg single	90.0–100	NA	[63]
	Taeniases	400 mg/day×3 days	75.7–100	NA	[50]
		400 mg b.i.d.×3 days	70.0–95.0	NA	[13,21]
	Hymenolepiasis	400 mg/day×3 days	28.5–100	NA	[50]
		400 mg b.i.d.×2 days	66.7	NA	[13]
Mebendazole	Ascariasis	500 mg singlea	95.0	96.0–100	[10]
		100–300 mg single	89.7–96.7	98.6–99.9	[49]
		100 mg b.i.d.×3 days	92.0–100	91.0–100	[10,49]
	Hookworm infections	500 mg single	15.0–17.6	0–98.0	[10,44]
		100 mg b.i.d.×3 daysa	52.0–80.0	41.0–100	[8,10]
	Trichuriasis	500 mg single	27.9–36.0	66.0–93.0	[10,44]
		100 mg b.i.d.×3 daysa	33.7–80.0	67.1–99.0	[10,58]
	Enterobiasis	100 mg singlea	90.0–100	NA	[8]
		25–200 mg single	62.0–100	NA	[4]
		100–400 mg single	90.0–100	NA	[63]
	Taeniases	500 mg single	50.0	NA	[23]
		500 mg/day×3 days	100.0	NA	[23]
	Hymenolepiasis	100 mg t.i.d.×3 days	18–40	NA	[71]

^aRecommended dose by WHO [45].

NA, not applicable.