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. 2021 Jun 30;59(3):189–225. doi: 10.3347/kjp.2021.59.3.189

Table 3.

Albendazole and mebendazole for treatment of human cysticercosis and hydatidosis

Drug Disease & parasite Regimen Efficacy Remark References
Albendazole Neurocysticercosis (metacestode of Taenia solium) 15 mg/kg/day×7–15 days Effective Parenchymal, subarachnoid, and ventricular cysticerci Combined with steroids [22,158,159]
Cutaneous cysticercosis (metacestode of Taenia solium) 15 mg/kg/day×28 days Satisfactory Combined with steroids [163]
Cystic echinococcosis (hydatid of Echinococcus granulosus) 400 mg b.i.d.×3–6 months with 14 days of break Fairly good Combined with PAIRa [174]
Alveolar echinococcosis (hydatid of Echinococcus multilocularis) 400 mg b.i.d.×2–3 years with 14 days of break Fairly good Minimum 2–3 years, but probably lifelong [174]

Mebendazole Neurocysticercosis (metacestode of Taenia solium) Mebendazole plus praziquantel recommended - - [164]
Cutaneous cysticercosis (metacestode of Taenia solium) Mebendazole plus praziquantel recommended [164]
Cystic echinococcosis (hydatid of Echinococcus granulosus) 50–70 mg/kg/day× 6–24 months Fairly good Lower efficacy than albendazole [172,186]
Alveolar echinococcosis (hydatid of Echinococcus multilocularis) 45–48 mg/kg/day×13 years Seemingly good May be parasiticidal [189]
a

PAIR consists of puncture, aspiration, injection of scolicidal agent, and reaspiration.