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. 2021 Jun 21;9:685873. doi: 10.3389/fcell.2021.685873

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Copyright © 2021 Zhang, Yan, Liu, Chen, Li, Tang, Li, Duan and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification and functional analysis of hAFSC-exo-miRNAs. (A) Target mRNA prediction of hAFSC-exo-miRNAs using Gene Ontology analysis; the TGF-β signaling pathway was highly related to myofibroblast formation. (B) The miRNA–mRNA interaction network of hAFSC-exo-miRNAs and their predicted targets. (C) Primary miRNAs in hAFSC-exo as measured by qRT-PCR analysis.