Table 5.
Intervention studies on the effects of protein intake during weight loss on REE
| Study | Proband characteristics | Protein intake | Energy restriction | Weight reduction, kg | REE change |
|---|---|---|---|---|---|
| Tang et al. [10] | 43 men Age >21 years BMI 25–39.9 |
1.4 g/kg BW/day 0.8 g/kg BW/day |
−750 kcal/day from REE × 1.5 estimated by the Harris-Benedict formula 12 weeks | −9.1±0.7 (P) −10.6±0.6 (C) Group difference n.s. |
−104±77 kcal/day (P) −171±71 kcal/day (C) Group difference n.s. |
| Luscombe et al. [37] | 36 subjects Male and female Age 34–65 years Hyperinsulinemia BMI 27–43 |
27 EN% 16 EN% |
−30% from TEE (measured via the bicarbonate-urea method) 16 weeks, thereof 4 weeks of balanced energy | −7.9±1.1 (P) −8.0±0.7 (C) Group difference n.s. |
−650±171 kJ/day (P) −780±132 kJ/day (C) Group difference n.s. |
| Baba et al. [38] | 13 men Hyperinsulinemia BMI >31 |
45% 12% |
80 E% from REE (measured by indirect calorimetry) 4 weeks | −8.3±0.7 (P) −6.0±0.6 (C) Group difference p < 0.05 |
−132±51 kcal/day (P) −384±85 kcal/day (C) Group difference p < 0.05 |
TEE, total energy expenditure; n.s., nonsignificant; EN%, percentage of energy; P, protein group, C, control group; BW, body weight.